Endometriosis Support

NAC provides the antioxidant foundation: NAC at 600mg supports glutathione production, reduces oxidative stress, and exerts antiproliferative effects on endometriotic tissue (Lagana et al., 2023).

N.A.C
The most directly researched supplement for endometriosis.

Omega Capsules
EPA omega-3 competes with arachidonic acid for cyclooxygenase enzymes, producing Series 3 prostaglandins (PGE3) instead of pro-inflammatory PGE2.

DIM-CDG
DIM (diindolylmethane) supports Phase I estrogen hydroxylation toward 2-OH metabolites.

InflamaQ
Curcumin modulates NF-kB, the master inflammatory transcription factor active in endometriotic lesions.

Magnesium Powder
Magnesium bisglycinate supports smooth muscle relaxation (directly reducing uterine contractility), modulates prostaglandin synthesis, and provides nervous system calming for centrally sensitized pelvic pain.

✓ Who this is for

Women diagnosed with endometriosis who are looking for evidence-based nutritional support alongside their medical management. Women experiencing endometriosis symptoms - pelvic pain, dysmenorrhea, dyspareunia - who want to address underlying inflammatory and hormonal drivers through nutrition.

✗ Who this is not for

People on anticoagulant medications (omega-3 and NAC both have mild anticoagulant properties; combined with prescription anticoagulants, this requires prescriber supervision). People with active peptic ulcers or history of GI bleeding (NAC may increase gastric acid at high doses).

Morning with food: Omega Capsules (1 softgel), DIM-CDG (2 capsules). With lunch or dinner: InflamaQ (2 capsules).

Prostaglandin shift from omega-3: 4-8 weeks of consistent daily use. Magnesium and pain modulation: 2-4 weeks.

What supplements are evidence-based for endometriosis?

NAC (N-acetyl cysteine) has the strongest direct clinical evidence - Lagana et al. (2023) found significant reductions in dysmenorrhea, dyspareunia, and chronic pelvic pain scores, along with endometrioma size stabilization, at 600mg taken 3 times daily for 3 consecutive days per week over 3 months.

Can I take these supplements alongside hormonal birth control or Lupron for endometriosis?

Omega-3, magnesium, and NAC are generally compatible with hormonal endometriosis treatments. DIM-CDG, however, modulates estrogen metabolism pathways and should be discussed with your prescriber before combining with hormonal birth control, progestins, or GnRH agonists like Lupron.

How does the NAC dosing work in this bundle - why is it cyclic?

The Lagana et al. (2023) dosing protocol - 600mg three times per day for three consecutive days per week, repeated each week - is based on NAC's pharmacokinetic properties.

How is this different from the That Time of the Month bundle?

That Time of the Month addresses typical menstrual symptoms in women without endometriosis - cramping, heavy flow, iron loss, mood shifts. This bundle is specifically designed around the four biological mechanisms of endometriosis: oxidative stress and lesion proliferation (NAC), estrogen-driven tissue growth (DIM-CDG), prostaglandin-driven pain (omega-3), and the chronic inflammatory environment (InflamaQ).

NAC at the recommended cyclic dose (600mg x 3 doses x 3 days/week) is well-tolerated; GI sensitivity has been reported at higher continuous doses. Do not combine NAC with nitroglycerin (interactions with nitric oxide).

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Consult your healthcare provider before starting any supplement regimen.